Proč migréna zahání své oběti do tmy
http://www.osel.cz/index.php?clanek=4829
Par poznamek z orig člaku :
-chemicals that are thought to be released in a migraine attack -
serotonin, prostaglandins and
histamine.
-hypersensitive that they were stimulated by signals
100-times smaller than what’s required to induce any kind of activity in this nerve under normal conditions.
-One of the interesting things that we heard once we start talking to patients is during migraine attacks they
become aware of the space between their brain and the skull. Nobody under normal condition can say that.
-But the nerves in the spinal cord which process the incoming information before the messages are sent to the brain. They become activated and hyper responsive too.
Professor Burstein Now here is the biggest surprise so far. Because the
nerves in the spinal cord receive sensory signals from two sources, not only from inside the head but also from outside the head like from the skin area around the eyes the per-orbital area, the skin around the temples and the skin area around the eyes. Now what the animal studies showed us is that if we touch with the mildest forces the skin around the eyes, the nerves in the spinal cord fire or respond at the same intensity that they respond if we stimulate it with the most noxious stimulus. Now normal signals will transmit the wrong signal. They are translated from non-noxious signals into noxious ones. So, from non-painful into painful signals.
-They found that when people have a migraine headache,
nearly 80% of them have hypersensitive skin over the area where they feel the pain - round the eye or to the side of the head.
-skin to like, you know, skin temperature is 32 degrees centigrade, it’s enough to warm it to 36 and it would be painful during migraine. While in the absence of migraine you need to warm it to 45, 46, 47 before they feel pain and they want to stop it.
-Like they can’t wash their hair, they can’t wear earrings, they can’t wear glasses because it hurts them on the contact side, they can’t breathe through their nose because the temperature of the air is colder when they breathe through their nose and it hurts them inside their nose, like they can’t take a shower in the morning because during migraine the water feels like needles when it touches their head. Like women can’t use hairpins to keep their hair together, it’s too painful. They had to cut their hair shorter because during migraine long hair, the weight of the hair was enough to induce pain in the scalp.
Tenhle članek poskytl docela dost zajimavejch souvislosti a par napadu ale neurochemie je dodt složita bude potraba to prozkoumat vic do hloubky
*pri bolesti hlavy by mělo pomoct blokovat modry světlo (viz clanek o serotoninu) melo by snižit produkci serotoninu a spustit jeho preměnu na melatonin tim snižit senzitivitu a bolest
*dalši z latek co tam podporuje tu hypersenzitivitu je hystamin takže by mhly pomct antihystaminika- prašky proti alergiji
*pak už je spiš vic otazek než odpovedi ty samotny 2 latky na to stačit nebudou bežne serotonin docela podoruje dobry pocity ,pohodu ,bdělost hystamin -bdelost..
neco jinyho se musi rozhodit bude potreba zjistit co určite co bude mit i neco společnyho z stresovejma hormanama ,negativni energiji,filtraci informaci v thalamu ,prefronatlnim kortexem ten jen zjistit co .
*samotna hypersenzitivita je pomerne zajima umožnila by vnimat mnohem vic než normalně jen ji to chce nejk držet pod kontrolou , už driv sem zjistil že pri negtivni nergiji je citit jkde je telo oslabeny tohle by častečne vysvetlilo proč telo se najdnou stane mnohem cilivejši na tyto problemy a ukaže se kde sou jeste to chce najit ten vypinač